Story Behind the picture

The picture above was taken from “The Sepsis Study” that was started in late 2013 in Thailand. The study was then continued in Vietnam and Indonesia with supports from Ministries of Health of Indonesia, Thailand and Vietnam, as well as the South East Asia Infectious Disease Clinical Research Network (SEAICRN) global partners, including the US National Institute of Allergy and Infectious Diseases, the Wellcome
Trust and the World Health Organization (WHO). Conducted by the SEAICRN, the sepsis study seeks to identify the causes and outcomes of sepsis, improve its treatment, and help public health authorities and medical researchers across South East Asia to better respond to other potentially deadly public health threats in South East Asia as new infectious diseases emerge. Other study which was also supported by WHO, are AFIRE (Acute febrile illness that require Hospitalization),and Tripod (Tuberculosis research of Ina-respond on drug resistance.

Our vision is to become Indonesia’s leading center of excellence in the field of clinical microbiology, which is scientific cultured, high quality, and represent the soul of local wisdom by 2020.These are the eminent services at the Microbiology Department :

• Provide microscopic examination: Direct examination, gram staining, acid fast bacillus staining (AFB), staining for specific microorganism : Diphteria, yeast and other fungi, bacterial spore, capsule etc.
• Dark field microscope for direct observation of Leptospira.
• Culture and identification of aerob and non aerobic bacteria, including fastidious microorganism, such as Helicobacter pylori, S.
  Pneumoniae etc
• Antibiotic susceptibility test of bacteria
• Antifungal susceptibility test of fungi
• Examination of drinking water
• To explore the potency of antimicrobe for new drug, including antibacteria, antifungal and anti TB
• Examination of antigenemia and Viruria of Cytomegalovirus (CMV)
• Molecular identification for Rotavirus
• Molecular identification of MDR TB (XpertMTB/RIF) and Drug Susceptibility Test of M.Tuberculose
• Identification Biofilm-Forming capability of microorganism
• Monitoring the numbers of germs in the Hospital
• Monitoring career / food born diseases on nutritional installation staff/ Food Company
• Monitoring of microbial hospital waste management

In addition, many collaboration research were performed in our department, such as the following research in virology:

• Surveillance Rotavirus causes diarrhea,“Extension for Hospital-Based Surveillance and strain characterization of Rotavirus Diarrhoea in Indonesia” held since 2009 until now, in collaboration with WHO-SEARO. This project aimed to develop vaccines against rotavirus in the stage of clinical trials Phase IIb, in collaboration with the Murdoch Children Research Institute and PT. Biofarma.
• Dengue virus, “Genotyping and phenotyping of dengue virus to Predict the severity and clinical manifestation of dengue virus infection” and “Association of polymorphisms of DC-SIGN (CD209) Carbohydrate Recognition Domain with Dengue Virus Infection.”
• National Consortium Dengue Vaccine Development. The development of recombinant protein PRM / E of dengue virus isolates locally.
• Identification of secondary metabolites of fungi Actynomycetes that have potential anti-dengue.
• IDAMS (International Research Consortium on Dengue Risk Assessment, Management and Surveillance)

Bacteriology research:

• Comparison of the potential combinationof imipenem and other antibiotics with a time-killing curve test, cheker board and E-test for antibiotic multiresistant isolates of Acinetobacterbaumannii
• Evaluation of the use of Xpert MTB/RIF in diagnosing TB for children: Operational research (funded by the Global Fund)
• National Program of TB care: Lab examination of TB MDR and TB HIV (supported by the Global Fund)
• The Prevalence of CLABSI (Central line associated blood stream infection) among patient in NICU, Sardjito hospital (in collaboration with BioMedical Engineering Dept, UMCG, The Netherlands)
• Antibiotic resistance in gram-negative ESBL,AmpC and MBL clinical isolates of Pseudomonas sp.

Mycology (Fungi) research:

• Antifungal effects and its mechanism: (1) -N-2-metoksibenzil-1,10-fenantrolinium bromide on planktonic cells and biofilms of Candida albicans cells
• Characteristics of virulence factors in C. albicans